Toxemia is a genuine confusion of the second 50% of human pregnancy, which can effectsly affect the quick and long haul wellbeing of the mother and the child . In this examination we attempted to demonstrate that we can utilize pentraxin-3 as early indicator of preeclapmsia. Patient and strategies: This examination included 289 cases separated toward the finish of following up into two gatherings before investigation of blood tests G I: pregnant ladies who created toxemia (n=17) GII: pregnant ladies who didn't created toxemia (n=272). Maternal blood test gathered and put away at the hour of the ultrasound assessment (between8-10weeks).Maternal blood tests centrifuged and serum put away at - 80C until examination what began in the wake of following up of all tolerant . Examination performed blinded to the pregnancy result. Results: serum pentraxin3 was essentially higher in ladies further created toxemia contrasted with these ladies who not created toxemia later on ( 27.1± 15.6 versus 2.5± 4.7 ,p esteem <0.001). the seriousness of toxemia and serum pentraxin 3, our outcomes brought up there was a huge connection between's the seriousness of toxemia and the degree of pentraxin. End: serum pentraxin 3 might be utilized as a screening test as ahead of schedule as in first trimester of pregnancy for early recognition of toxemia.