Laparoscopic without drawbacks associated with two complications, bile duct injury and complications due to spillage of stone/bile within the peritoneal cavity . This study aimed to evaluation of different short-term complications of bile and gallstones spillage during laparoscopic cholecystectomy.This was a prospective comparative study carried on 100 patients, divided into 2 groups: group A :(50) control random doing laparoscopic cholecystectomy without gallbladder perforation ; group B:(50) cases doing laparoscopic cholecystectomy with gallbladder perforation and bile and gallstones spillage. The postoperative outcome was monitored during outpatient visits. The amount and nature of drained fluid were recorded daily. Postoperative complications including pain, peritonitis, and ileus were recorded. We used 3^rd generation cephalosporin for therapy of infection, and. Wound dressing was standard in all groups. Perforation Group was significantly longer than non-perforating group regard Duration of post-operative pain while regard Duration of post-operative ileus it was longer also in perforating group but not significantly. Perforation Group was significantly associated with Bile and stone spillage, abdominal collection and Re operate to treat complications, regard Converted to open surgery and Port site infection they were also associated with Perforation Group but not significantly. Intraoperative spillage of bile and gallstones during laparoscopic cholecystectomy can cause more postoperative pain,increase operative time,ileus and port site infection,which consequently increase the total time of hospitalization, inderminig.