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169132

Urinary MicroRNA96 as Biomarkers for Bladder Cancer Detection

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Last updated: 28 Dec 2024

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Abstract

Bladder malignancy is viewed as the fifth most basic disease with expanded disorder and demise. As of late, incessant examinations showed that microRNAs are arising as indicative biomarkers for bladder malignancy. Explicit miRNA profiles have been distinguished for a few examples from patients with bladder malignancy. MicroRNAs are noncoding RNA particles of around 23 nucleotides that assume significant parts in different strides during the movement of bladder malignant growth. Here, we audit the declaration of miRNAs and their organic capacities, guideline, and clinical ramifications in bladder malignant growth. Either downregulation or upregulation of miRNAs happens in bladder malignant growth through epigenetic changes or imperfections of the biogenesis mechanical assembly. Liberation of miRNAs is engaged with cell cycle capture, apoptosis, multiplication, metastasis, drug obstruction, and different capacities in bladder malignancy. Various miRNAs, have been related with tumor type, stage, or patient endurance, and miRNAs may be created as demonstrative or prognostic markers. A superior comprehension of the jobs of miRNAs in bladder malignant growth will reveal insight into the sub-atomic systems of bladder disease.

DOI

10.21608/bjas.2021.169132

Authors

First Name

A.H.

Last Name

Attia

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Affiliation

Biochemistry & Molecular Biology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

O.A.

Last Name

Abdullah

MiddleName

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Affiliation

Biochemistry & Molecular Biology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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First Name

M.A.

Last Name

Hassanien

MiddleName

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Affiliation

Urology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

S.K.

Last Name

Eliwa

MiddleName

-

Affiliation

Biochemistry & Molecular Biology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

-

First Name

H.E.

Last Name

Ahmed

MiddleName

-

Affiliation

Biochemistry & Molecular Biology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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Volume

6

Article Issue

1

Related Issue

24493

Issue Date

2021-01-01

Receive Date

2021-02-05

Publish Date

2021-01-01

Page Start

291

Page End

293

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_169132.html

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https://bjas.journals.ekb.eg/service?article_code=169132

Order

46

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Urinary MicroRNA96 as Biomarkers for Bladder Cancer Detection

Details

Type

Article

Created At

23 Jan 2023