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169127

Chemerin as a Biomarker of Acute Coronary Syndrome

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Last updated: 28 Dec 2024

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Abstract

Intense coronary disorder (ACS) is a condition (set of signs and indications) because of diminished blood stream in the coronary courses with the end goal that piece of the heart muscle can't work appropriately or kicks the bucket. The point of study is to assess chemerin levels in patients with intense coronary disorder. The investigation included 100 subjects who were ordered into two gatherings; control bunch which included 20 subjects with typical coronary discoveries, and cases bunch which included 80 cases with ACS (counting STEMI, NSTEMI, and UA). All cases and controls were exposed to finish history taking, careful actual assessment, and routine lab examinations. Likewise, serum chemerin were estimated for all cases and controls. The mean age of the included subjects was 55.99 and 56.2 years for ACS and control bunches individually. Guys spoke to 55 and 52.5% of cases in the two gatherings individually, with no measurably huge distinction between the two gatherings (p=0.448). Serum chemerin level was fundamentally higher in the ACS gathering (268.8 ng/ml versus 115 ng/ml in controls – p < 0.001). On separating ACS cases into 3 subtypes, there was mellow huge distinction between STEMI, NSTEMI, and UA (p = 0.086). The best cutoff purpose of Chemerin to foresee the event of ACS was >249.5 ng/ml with 74.6% affectability, 82% particularity, 78% PPV, 72% NPV and precision of 72%. Chemerin was more touchy than troponin in distinguishing cases with ACS.

DOI

10.21608/bjas.2021.169127

Keywords

Chemerin, Coronary Syndrome, ACS, troponin

Authors

First Name

T.H.

Last Name

Abo Elazm

MiddleName

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Affiliation

Cardiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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First Name

Y.M.

Last Name

Ismail

MiddleName

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Affiliation

Clinical,Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

-

First Name

H.H.

Last Name

Ebaid

MiddleName

-

Affiliation

Cardiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

-

First Name

M.S.

Last Name

Darwish

MiddleName

-

Affiliation

Cardiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

-

First Name

M.M.

Last Name

Taha

MiddleName

-

Affiliation

Cardiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

-

Orcid

-

Volume

6

Article Issue

1

Related Issue

24493

Issue Date

2021-01-01

Receive Date

2021-02-05

Publish Date

2021-01-01

Page Start

279

Page End

284

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_169127.html

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https://bjas.journals.ekb.eg/service?article_code=169127

Order

44

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Chemerin as a Biomarker of Acute Coronary Syndrome

Details

Type

Article

Created At

23 Jan 2023