Immune thrombocytopenia (ITP, formerly idiopathic thrombocytopenic purpura) is an acquired disease characterized by immune-mediated destruction of normal platelets and suppression of platelet production that is associated with variable bleeding symptoms. This review study is intended to dissect subtleties of safe thrombocytopenia (ITP) cases, assessment of treatment modalities and result among kids in Benha. Also, to decide the prognostic variables as rules for new cases at diagnosis. Techniques: One hundred and 50 instances of youngsters who were analyzed ITP and followed up in pediatric hematology department in Benha University Hospitals were incorporated. All the patients were exposed to Full history taking, Through clinical assessment, Laboratory examinations: Complete blood picture, Bone marrow sample (for indicated cases only) were done to affirm the diagnosis of ITP. Results : Of 150 patients, 79(52.7%) were guys, and 71(47.3%) were females, 59.5% of cases had intense ITP, 11% had persistent ITP, and 29.5% had ongoing ITP, we merged the first two groups. there was a critical contrast in platelet count between acute+persistent and ongoing ITP, the median platelet count was 12.4 x103 (range 2-54)in acute+persistent cases. We found that middle platelet count at finding was fundamentally lower for patients who showed acute+persistent ITP with middle platelet tally of 21.5 x103 (range 2-49) (p < 0.001), We found young age had favorable outcome (p < 0.001).