Platelet-rich plasma (PRP) is characterized as a segment of the plasma part of autologous blood having a platelet fixation above standard. PRP likewise has been alluded to as platelet-improved plasma, platelet-rich concentrate, autologous platelet gel, and platelet releasate. To research the advantages of infusing platelet rich plasma in mending of constant leg ulcers. This is a solitary – focus, planned, randomized, controlled examination that was directed in General Surgery Department, Faculty of Medicine, Benha University incorporating 100 patients giving persistent leg ulcers and introduced to us between January 2018 to June 2018. This investigation was completed in 100 patients with ongoing leg ulcers were remembered for this examination, patients were arbitrarily partitioned in two equivalent gatherings An and B. The magnificent outcomes appeared in ongoing investigations have just served to affirm the great results depicted in our examination. In ten patients that we treated, the outcomes got following consummation of the uses of PRP were acceptable or phenomenal. The utilization of PRP in remedial cycles identified with Plastic, Reconstructive and Esthetic Surgery is presently a genuine alternative in generally open and private emergency clinics in numerous nations; circumstance that shows the advances that have happened over ongoing years in tissue recovery treatment.