One in each eight ladies created bosom malignancy of which roughly 60% are to be dealt with carefully for essential bosom tumor resection and axillary lymph node(L.N) arranging. The point of this postulation is to assess the useful and oncological noteworthiness of conservation of intercostobrachial nerve during axillary lymph hub analyzation in instances of bosom malignancy and its effect on Post Mastectomy Pain Syndrome. forty patients were remembered for this imminent investigation were devided into 2 equivalent gatherings. 20 patients were incorporated into the ICBN conservation bunch A. In gathering B, 20 patients were incorporated as control where this nerve was separated. In all the cases, ICBN was recognized intraoperatively. The torment appraisal was done on the first day, following multi month and following 3 months post-operatively. It was discovered that, 75% of the patients were asymptomatic following 3 months of follow up in ICBN safeguarding gathering (bunch A) and 60% in the nerve segment gathering (bunch B ) (p < 0.01). There was a slight expansion in the all out season of a medical procedure in gathering A, however it was not huge and there was likewise no critical distinction in the quantities of axillary lymph hubs analyzed between the two gatherings. safeguarding of ICBN is an attainable and astute approach to diminish PMPS in bosom malignancy patients without bargaining usable time or nearby pace of repeat.