Foundation: The epilepsies are persistent neurological issues in which groups of nerve cells, or neurons, in the mind now and then sign strangely and cause seizures. During a seizure, numerous neurons fire (signal) simultaneously – upwards of 500 times each second, a lot quicker than ordinary. This flood of extreme electrical action occurring simultaneously causes automatic developments, sensations, feelings, and practices and the impermanent unsettling influence of typical neuronal action may cause lost mindfulness. Epilepsy influences patients, all things considered, races, and ethnic foundations. As indicated by the National Institute of Neurological Diseases and Stroke (NINDS), about 2.3 million grown-ups and in excess of 450,000 kids and teenagers in the United States have epilepsy. Point of the Work: to evaluate the mental comorbidity and personal satisfaction in patients with epilepsy through poll 30 patients at the Neurology Unit in Pediatric Department in Benha University.Patients and Methods: At the Neurology Unit, Pediatric Department, Benha University Hospitals, the variables adding to mental comorbidity in epilepsy and to survey the effect of mental co-grimness on personal satisfaction were resolved in 30 patients with epilepsy and 30 benchmark group . The essential end purpose of this investigation is to distinguish the mental comorbidity and personal satisfaction in patients with epilepsy and their effect on personal satisfaction. Results: there is huge distinction between the contemplated bunches with respect to the downturn and tension evaluations, where 86.7% of the controls had no downturn contrasted with 0% of the patients, while just 13.3 % of them had gentle evaluation contrasted with 43.3% of the patients. Then again, 30% and 26.7% of patients endured moderate and extreme sorrow individually contrasted with 0% of the controls. End: mental comorbidity has solid effect on personal satisfaction in persistent with epilepsy.