Tension problems are one of the most widely recognized mental issues. Up to 20% of grown-ups are influenced by tension issues every year. Nervousness issue produces dread, stress, and a consistent sentiment of being overpowered. It is additionally portrayed by steady, over the top and ridiculous stress over ordinary things. Substance reliance is an enormous worldwide general medical condition. Substance reliance is related with word related inability, expanded danger of burdensome and crazy issues, social weakness, detainment, and physical medical conditions. The reasons for drug misuse and reliance are not known, however past information propose that danger variables might be recognizable generally right off the bat throughout everyday life, even before the commencement of utilization and misuse. Epidemiological examinations have reliably settled high comorbidity between mental problems and substance use issues. The high commonness of comorbidity between substance use issues and other psychological instabilities doesn't really imply that one caused the other, regardless of whether one showed up first. Social and passionate issues may not be extreme enough for an analysis purported subclinical manifestations, and these subclinical emotional well-being issues may incite substance misuse. Comorbidity or the co-event of tension issues and substance use problem is normal. The commonness of comorbidity in the network and the mind boggling communications that happen between the two arrangements of issues should raise questions about the way in which we keep on managing every element independently, specialists need to consider these issues as an aspect of an entire complex marvels in which the two problems are firmly connected together. Accordingly, in trying to all the more likely comprehend the idea of comorbidities among nervousness and substance use issues, it is vital to analyze examples of the co-event of tension problems with substance use issues. Point of the examination: Evaluate the predominance of uneasiness issues in substance use issues and to explore the connection between explicit tension issues and substance use. This is a cross sectional enlightening investigation on patients going to the day by day outpatient enslavement center of El Matar Psychiatric Hospital. Various 200 patients with substance misuse issues were haphazardly picked. Assortment of the example was from the first of June 2017 till the first of December 2017. Patients were exposed to a full history taking, total physical and neurological assessment, mental appraisal, psychometric evaluation utilizing Hamilton Anxiety Rating Scale (HAM-A) and Drug screening in pee. Anxiety issues were found in 70.5% of substance misuse cases were 33% had a gentle degree uneasiness, 19% had a serious tension and 18.5% had moderate nervousness. The mean term of tension problem among substance misuse cases was 2.93 year. The most predominant tension issue among the substance misuse cases was alarm problem in 34% of cases, summed up uneasiness issue in 27.5%, agoraphobia in 20%, explicit fear in 18% and social fear in 15.5%.