Back ground: Trauma score are used to obtain a numerical description of the severity of an individual's injuries and clinical condition, which in turn is associated with prognosis. Trauma score that used in predicting mortality among polytraumatized patients could be anatomical or physiological or combined. The Injury severity score (ISS) is the most commonly used measure of injury severity. It is an anatomical scoring system that provides an overall score for patients with multiple injuries. Each injury is assigned an Abbreviated Injury Scale (AIS) score. The Revised Trauma score (RTS) is a physiological scoring system with high inter-rater reliability and demonstrated accuracy in predicting death. The present study aimed to study outcome value of RTS in comparison to ISS and try to find a relation between initial scores and their outcome. Fifty patients randomly collected presented to the Critical Care Departments. The Injury Severity Score (ISS) and Revised Trauma Score (RTS) was calculated ,the patients had a mean ± SD age of 37.04 ± 13.42 years. They comprised 42 males (84%) and 8 females (16%). The major mechanism of injury in polytrauma patient was road traffic accidents (76.0%). The majority of cases in the age group 20 to 49 (72%). Males were 3 times more affected than females. The most common cause of death was respiratory. RTS was better than ISS in predicting mortality among polytraumatized patients.