137139

Serum Interleukin 19 in Patients with Alopecia Areata

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Last updated: 05 Jan 2025

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Abstract

Alopecia areata (AA) is a typical ailment influencing the analgen period of the hair follicles. Interleukin (IL)- 19 is an individual from an IL-10 subfamily which additionally incorporates IL-20, IL-22 and IL-24. It normally shows as restricted, all around differentiated patches of going bald. It might present as single or different patches. The point of this examination was to survey the degree of serum of IL-19 in patients with AA to assess its part in AA pathogenesis and its conceivable connection with seriousness of the illness. Case control study included 30 patients experiencing AA notwithstanding 30 obviously sound people of coordinated age and sex as a benchmark group. Analysis of AA was made based on clinical discoveries and the seriousness of the sores will be evaluated by Severity of Alopecia Tool (SALT) score. The serum IL-19 levels estimated by chemical connected immunosorbent examine (ELISA). We found that all out AA bunch indicated fundamentally higher serum IL-19 when contrasted with control gathering. Higher IL-19 was essentially connected with dynamic cases. Likewise, it expanded steadily with seriousness. Something else, no noteworthy affiliations were found with respect to IL-19 level as indicated by sexual orientation, family ancestry, beginning, course, assortment, repeat and past treatment in AA gathering.

DOI

10.21608/bjas.2020.137139

Keywords

Alopecia Areata, Interleukin-19

Authors

First Name

A.A.

Last Name

Ebrahim

MiddleName

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Affiliation

Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

A.I.

Last Name

Mustafa

MiddleName

-

Affiliation

Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

W.A.

Last Name

Abd El-Haleem

MiddleName

-

Affiliation

Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

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First Name

A.E.

Last Name

Salah

MiddleName

-

Affiliation

Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

-

Orcid

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Volume

5

Article Issue

Issue 6 part (2)

Related Issue

20332

Issue Date

2020-09-01

Receive Date

2020-01-08

Publish Date

2020-09-01

Page Start

187

Page End

189

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_137139.html

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https://bjas.journals.ekb.eg/service?article_code=137139

Order

5

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Serum Interleukin 19 in Patients with Alopecia Areata

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Article

Created At

23 Jan 2023