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Glaucoma Diagnostic Accuracy of Ganglion Cell Inner Plexiform Layer Thickness Comparison with Peripapillary Retinal Nerve Fiber Layer

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Last updated: 28 Dec 2024

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Abstract

Glaucoma is an optic neuropathy characterized by progressive loss of retinal ganglion cells (RGCs) and their axons, eventually resulting in visual field loss. As glaucomatous visual misfortune is irreversible, early determination is significant; be that as it may, this can be trying because of enormous between singular variety in ordinary plate appearance, between onlooker contrasts in circle assessment, and absence of affectability of visual field testing because of physiological excess in retinal ganglion cell responsive fields. The reason for this investigation is to decide the symptomatic exhibition of macular ganglion cell–internal plexiform layer (GCIPL) thickness and to contrast it and that of peripapillary retinal nerve fiber layer (RNFL) thickness to segregate typical eyes and eyes with early glaucoma. 20 eyes with early glaucoma (case gathering) and 20 ordinary eyes (control gathering) were joined up with this examination and their RNFL and GCIPL boundaries were estimated utilizing Topcon 3D ghostly space OCT 2000. the GCIPL and RNFL were more slender and the vertical cup-to-circle width proportion was bigger in subjects with glaucoma than in typical subjects. What's more, aggregate and sub-par GCIPL values were the most exact for the analysis of early glaucoma. high hazard gathering and analyzed gathering of glaucoma ought to be catch up with RNFL and GCIPL thickness utilizing OCT.

DOI

10.21608/bjas.2020.136698

Keywords

Glaucoma, Ganglion cell, Plexiform Layer thickness, Retinal nerve fiber

Authors

First Name

A.F.

Last Name

Elsawy

MiddleName

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Affiliation

Ophthalmology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

H.M.

Last Name

Fayek

MiddleName

-

Affiliation

Ophthalmology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

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First Name

E.A.

Last Name

Mahmoud

MiddleName

-

Affiliation

Ophthalmology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

-

City

-

Orcid

-

Volume

5

Article Issue

Issue 5 part (2)

Related Issue

20313

Issue Date

2020-08-01

Receive Date

2020-01-07

Publish Date

2020-08-01

Page Start

273

Page End

278

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_136698.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=136698

Order

12

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Glaucoma Diagnostic Accuracy of Ganglion Cell Inner Plexiform Layer Thickness Comparison with Peripapillary Retinal Nerve Fiber Layer

Details

Type

Article

Created At

23 Jan 2023