136672

Study the Role of Interleukin-4, Interleukin-17 and Interleukin-35 in Diagnosis and Prognosis of Preeclampsia in Egyptian Patients

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Last updated: 05 Jan 2025

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Abstract

Toxemia is a genuine entanglement of pregnancy, which is the reason for 60,000 maternal passings every year around the world. Notwithstanding the notable maternal hazard factors, for example, hypertension, diabetes mellitus, antiphospholipid neutralizer condition, heftiness, maturing, and various pregnancies, ongoing investigations have distinguished the job of hereditary and immunological elements in the pathogenesis of toxemia. PE could prompt maternal and pre-birth dismalness. Imbalanced cytokine arrange and modified degrees of a few fiery and calming cytokines have been accounted for in PE The examination intended to evaluate the serum levels of IL-4, IL-17 and IL-35 in toxemia patients well as in normotensive pregnant women.Blood tests were gathered from 25 toxemia patients and 15 normotensive pregnant ladies. Serum levels of IL-4, IL-17 and IL-35 in totally examined bunches were controlled by an immunoenzyrnatic test. The outcomes indicated higher groupings of IL-17 in PE and huge contrast between PE cases and control gathering and no noteworthy distinction in IL4 and IL35. A critical positive relationship was found between serum IL-17 and negative connection with maternal age, gravidity state, SBP and DBP.

DOI

10.21608/bjas.2020.136672

Authors

First Name

A.M.

Last Name

Agha

MiddleName

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Affiliation

Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

A.M.

Last Name

Abdelrahman

MiddleName

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Affiliation

Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

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First Name

A.M.

Last Name

Thabet

MiddleName

-

Affiliation

Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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First Name

B.E.

Last Name

Sakr

MiddleName

-

Affiliation

Gynecology and Obstetrics Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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First Name

H.M.

Last Name

Ahmed

MiddleName

-

Affiliation

Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Volume

5

Article Issue

Issue 5 part (1)

Related Issue

20312

Issue Date

2020-07-01

Receive Date

2020-01-07

Publish Date

2020-07-01

Page Start

183

Page End

188

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_136672.html

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https://bjas.journals.ekb.eg/service?article_code=136672

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25

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Study the Role of Interleukin-4, Interleukin-17 and Interleukin-35 in Diagnosis and Prognosis of Preeclampsia in Egyptian Patients

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Article

Created At

23 Jan 2023