Skin inflammation vulgaris is a fiery procedure confined to the pilosebaceous units of the face, chest, upper arms, and back Podoplanin is a little film glycoprotein with an enormous number of O-glycoside chains and in this manner it has a place with mucin-type proteins. The point of this investigation was to uncover podoplanin job in the pathogensis of skin break out scars. case control study included 30 patients experiencing scarring skin inflammation vulgarisand 30 patients experiencing non-scarring skin break out vulgaris moreover, 20 clearly solid people of coordinated age and sex as a benchmark group. Conclusion of AV was made based on the patient's history and the run of the mill clinical highlights. The all out seriousness score was gotten from the worldwide skin break out evaluating framework (GAGS). The serum activin-A levels estimated by catalyst connected immunosorbent examine (ELISA) We found that all out skin break out Vulgaris bunch indicated essentially higher serum Podoplanin when contrasted with control bunch scarring subgroups demonstrated altogether higher serum Podoplanin when contrasted with non-scarring subgroup . No critical contrasts were found in serum Podoplanin fixation as per sexual orientation and other hazard factors in skin inflammation vulgaris gathering. (P esteem >.0.5). Higher BMI, positive family ancestry, smoking, higher recurrence of abundance sun presentation, expending high caloric eating regimen, overabundance stress, higher serum Podoplanin level were related with danger of Acne Vulgaris scarring in univariable examination. In any case, facing huge challenge factors into multivariable investigation uncovered that positive family ancestry and higher serum Podoplanin were considered as independant indicators for Acne Vulgaris scarring.