136329

Hyper Triglyceridemia Induced Pancreatitis in Children with Diabetic Ketoacidosis

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Last updated: 05 Jan 2025

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Abstract

Diabetic ketoacidosis (DKA) is one of the most serious complications of diabetes. In DKA, the deficiency of insulin activates lipolysis in adipose tissue releasing increased free fatty acid (FFA) , which accelerates formation of very low density lipoprotein (VLDL) in the liver. In extreme hypertriglyceridemia, there is an expanded danger of creating intense pancreatitis. This investigation expected to assess the serum level of triglycerides and serum level of lipase as serological markers for intense pancreatitis in kids with Diabetic Ketoacidosis (DKA). For this situation controlled investigation, subjects were arranged into 2 gatherings; quiet gathering: Included 50 sort 1 diabetic youngsters, Control gathering: included 30 clearly solid kids age and sexual orientation coordinated to Diabetic patients gathering. The current examination was directed on 50 youngsters with DKA. Their mean age was 6.4 years, they were 24 guys (48%) and 26 females (52%). Notwithstanding 30 sound benchmark group of coordinated age and sexual orientation. DKA indicated altogether higher TC, LDL, fundamentally lower HDL when contrasted with control gathering. TG was fundamentally higher in DKA bunch when contrasted with control gathering. DKA with AP demonstrated fundamentally higher TC, LDL, and altogether lower HDL when contrasted with DKA without AP. TG and lipase levels were altogether higher in DKA with AP when contrasted with DKA without AP subgroups.

DOI

10.21608/bjas.2020.136329

Keywords

hyper triglyceridemia, pancreatitis, Diabetic ketoacidosis

Authors

First Name

B.M.

Last Name

Hassanein

MiddleName

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Affiliation

Pediatrics Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

H.R.

Last Name

Omar

MiddleName

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Affiliation

Pediatrics Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

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First Name

W.A.

Last Name

Abdelhaleem

MiddleName

-

Affiliation

Clinical & Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

-

Orcid

-

First Name

A.M.

Last Name

Moussa

MiddleName

-

Affiliation

Pediatrics Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

-

City

-

Orcid

-

Volume

5

Article Issue

Issue 4 part (2)

Related Issue

20280

Issue Date

2020-07-01

Receive Date

2020-01-06

Publish Date

2020-07-01

Page Start

177

Page End

182

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_136329.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=136329

Order

1

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Hyper Triglyceridemia Induced Pancreatitis in Children with Diabetic Ketoacidosis

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Article

Created At

23 Jan 2023