Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production, altered keratinization, inflammation, and bacterial colonization of hair follicles by Propionibacterium acne, Neutrophil gelatinase associated lipocalin expression have been reported in several normal tissues where it serves to provide protection against bacterial infection and modulate oxidative stress. The aim of the work is to evaluate the serum level of neutrophil gelatinase in patients with acne. This might have been a cross sectional instance similar study, directed in the dermatology, Venerology What's more Andrology division Furthermore clinical pathology section from claiming Benha college Hospitals, the ponder might have been led for eighty subjects ordered under two groups: aggregation i comprised for Fivty patients with skin inflammation vulgaris Furthermore assembly ii comprised for thirty sound people matched for age, sex Also figure impostor list (BMI) might have been a chance to be included Similarly as the control group, serum level from claiming neutrophil gelatinase might have been be measured utilizing Enzyme-Linked safe sorbent test. Those outcomes uncovered that there might have been Exceedingly measurable huge Contrast the middle of Assemblies Concerning illustration view NGAL for higher values Around instance assembly. Our information include novel viewpoints of the part of NGAL in the pathophysiology about skin inflammation vulgaris patients. Further investigations will require on report card those useful part of NGAL on fundamental focus receptor Previously, skin inflammation vulgaris should uncover inventive medicine methodologies.