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Effect of Adding Sildenafil to Clomiphene Citrate Versus Clomiphene Citrate Alone on Endometrial Receptivity in un Ovulatory PCO Patients

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Last updated: 28 Dec 2024

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Abstract

Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disorder of unknown etiology, with a prevalence ranging from 8.7 to 17.8% in women of reproductive age. Evidence suggests that PCOS phenotype may vary widely and is most commonly observed in the post-pubertal period. The aim of this study is to evaluate the endometrial receptivity (thickness, pattern, Also endometrial blood flow) Furthermore pregnancy rate Previously, patients for unovulatory PCO dealt with by clomiphene citrate Besides sildenafil tablets acquainted orally Likewise contrasted with the individuals treated by clomiphene citrate alone. This similar ponder might have been completed On obstetrics What's more Gynecology Department, Sers el Layan general Hospital, Menoufia Governate, egypt. It incorporated fruitless patients. From the individuals going to the outpatient Also inpatient facility with those finding of PCOS for six months beginning from those time from claiming june 2019 will december 2019. Those endometrial thickness might have been statistically huge higher to gathering (A) Concerning illustration 46% needed endometrial thickness (7-10) the place to bunch (B) 56% required endometrial thickness (3-6). Those mono-laminar endometrial design might have been more pervasive to both gatherings half What's more 54% On gatherings (A) & (B) individually. No statistically critical distinction discovered Eventually Tom's perusing correlation between two patients' gatherings Similarly as views endometrial example. The utilization from claiming sildenafil Similarly as an enhancer from claiming endometrial thickness serves patients for PCOS infertility, and counteracts poor people impact about clomiphene alone because of dainty endometrium. Sildenafl fundamentally expanded uterine blood flow for anovulatory patients of PCOS with clomiphene citrate disappointment. Sildenafl also expanded pregnancy rate to patients for PCOS and succeed the impact from claiming clomiphene alone. Further investigations ought further bolstering blanket this issues later on may be prescribed.

DOI

10.21608/bjas.2020.135859

Keywords

PCOs, Sildenafl, Clomiphene, Anovulatory, Endometrial

Authors

First Name

H.I.

Last Name

Mohamed

MiddleName

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Affiliation

Obstetrics , Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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First Name

M.A.

Last Name

EL-Noury

MiddleName

-

Affiliation

Obstetrics , Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

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Orcid

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First Name

A.S.

Last Name

Soliman

MiddleName

-

Affiliation

Obstetrics , Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

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City

-

Orcid

-

First Name

M.S.

Last Name

Sadek

MiddleName

-

Affiliation

Obstetrics , Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Email

-

City

-

Orcid

-

First Name

S.M.

Last Name

Abd-Elazim

MiddleName

-

Affiliation

Obstetrics , Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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City

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Orcid

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Volume

5

Article Issue

Issue 3 part (1)

Related Issue

20232

Issue Date

2021-03-01

Receive Date

2020-01-05

Publish Date

2021-03-01

Page Start

49

Page End

54

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_135859.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=135859

Order

10

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Effect of Adding Sildenafil to Clomiphene Citrate Versus Clomiphene Citrate Alone on Endometrial Receptivity in un Ovulatory PCO Patients

Details

Type

Article

Created At

23 Jan 2023