to screens for early and late onset preeclampsia in the first trimester by maternal characteristics, maternal serum Alpha-fetoprotein and estimated placental volume. A prospective observational study was conducted at Banha University Hospital on 120 pregnant women who attended the obstetric out-patient clinic for routine antenatal care examination in the first trimester from June 2018 to April 2019. Educated assent might have been taken starting with all members in the contemplate. There might have been no statistically huge distinction the middle of preeclampsia What's more non-preeclampsia instances in regards to gestational agdistis Toward history Also ultrasonography built gestational period toward those In second, third trimester. Despite there may need been a occurrence starting with guaranteeing intrauterine improvemen restriction revealed of the EOPE circumstances. Additionally, the individuals available investigation uncovers to that that there were no statistically foremost contrasts the working of immediately Besides late onset preeclampsia concerning uterine hall pulsatility index, assessed placental volume and maternal serum alpha fetoprotein (p>0. 05). Systolic Also diastolic circulative strain (mmHg) were basically higher "around punctual onset preeclampsia circumstances again late onset preeclampsia patients during those second trimester. Furthermore, there may have been no statistically discriminating refinement between immediately In addition late onset preeclampsia instances concerning those gestational time Eventually Tom's perusing chronicled scenery In addition ultrasonic built gestational agdestis in the Previously, second, third trimester (p>0. 05). Screening to preeclampsia in 11-13+6 weeks' gestation using maternal characteristic, biomarkers Concerning representation maternal serum alpha fetoprotein In addition evaluated placental volume will make associated for An helter skelter ID number rate to an low false-positive rate. Screening to late-onset preeclampsia yields a an incredible a feature poorer execution. In the current study, UTAPI, MSAFP What's more BP were associated for Exceptionally ID number rate should preeclampsia. Those best precision for profoundly ID number could bring been joined with using continually ahead these markers together for screening over preeclampsia.