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135750

Role of Colour Doppler Ultrasound in the Diagnosis and Grading of Liver Cirrhosis Compared with Transient Elastograpgy (Fibroscan)

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Last updated: 28 Dec 2024

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Abstract

The purpose of this study was to determine the morphological changes in hepatic vasculature and the flow hemodynamics in portal vein, hepatic veins and hepatic artery using various Doppler parameters in cirrhotic patients and to evaluate the variation in Doppler flow hemodynamics within cirrhotic livers as compared to liver stiffness measured by transient elastography. Study sample of 100 eligible patients with compensated liver cirrhosis were enrolled. All were examined with a pulsed Doppler flowmeter with a 3.75 MHz convex and sector probe. Liver texture, splenic size, portal and splenic vein diameters, portal vein velocity, hepatic artery resistive index and waveform of the hepatic vein were evaluated in all subjects comparing results with liver stiffness measured by transient elastography. All the data were collected, tabulated and statistically analyzed using an IBM personal computer with Statistical Package of Social Science version 22. The mean age of the patients was found to be 51.8 ± 10.2 years. The mean value of liver stiffness was 39.7 ± 18.0 kPa. The echotexture of liver was coarse with irregular margin in 69 patients (69.0%), coarse with smooth margin in 24 patients (24.0 %) and normal in 7 patients (7.0 %). The size of spleen was enlarged in 92.0 % of patients. Portal vein diameter was enlarged in 66.0 % of patients. Portal vein velocity shows abnormality in 65.0 % of patients. Hepatic vein waveform in 7.0% of patients was triphasic and non-triphasic in 93.0%. Hepatic artery restrictive index increased above normal range in 69.0 % of patients. Splenic vein diameter was enlarged in 92.0 %. There were statistically highly significant relations (P value < 0.001) between liver stiffness measured by transient elastography and liver texture, hepatic vein waves in colour Doppler US. A highly significant negative correlation (P value < 0.001) was found between Fibroscan results and portal vein velocity in our included cirrhotic patients. Fibroscan results had highly significant positive correlations (P value < 0.001) with splenic size, portal vein diameter, HARI and splenic vein diameter. Colour Doppler US play an important role in the diagnosis of the morphological changes in hepatic vasculature and the flow hemodynamics in portal vein, hepatic veins and hepatic artery. Fibroscan could predict changes in intrahepatic vascular resistance and it improves the accuracy of Doppler US in the detection of cirrhosis.

DOI

10.21608/bjas.2020.135750

Keywords

Liver cirrhosis, Doppler, Hepatic vein, Portal Vein, Hepatic artery, FibroScan

Authors

First Name

E.M.

Last Name

Elshaer

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Affiliation

Radiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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First Name

H.M.

Last Name

Khater

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Affiliation

Radiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Orcid

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First Name

A.F.

Last Name

Yousief

MiddleName

-

Affiliation

Radiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

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Volume

5

Article Issue

Issue 1 part (1)

Related Issue

20062

Issue Date

2020-01-01

Receive Date

2020-01-05

Publish Date

2020-01-01

Page Start

67

Page End

74

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_135750.html

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https://bjas.journals.ekb.eg/service?article_code=135750

Order

9

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Role of Colour Doppler Ultrasound in the Diagnosis and Grading of Liver Cirrhosis Compared with Transient Elastograpgy (Fibroscan)

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Article

Created At

23 Jan 2023