Peste des petits ruminants (PPR) is a highly contagious disease of domestic and wild small ruminants. According to Office international des epizooties  (OIE), it is now recognized as a disease of great economic importance, causing huge annual losses in farm animals. The present study recorded the current situation of PPR virus disease in some Egyptian Governorates in the period between years 2014 to 2019. A total of 432 swabs (nasal, ocular and mouth), 100 tissue samples (lung, spleen, intestine and lymph node were tested by immuno- capture ELISA for detection of PPRV antigen revealing that 133 (30.7%) of swabs and 38 (38%) of tissues were positive. Out of 1339 serum samples were tested by competitive ELISA (cELISA) for detection of PPRV antibodies, 853 (63.7%) were positive. The results showed that goat more sensitive for infection of PPR virus than sheep and the viral antigen detection increase in winter more than other seasons. Also the results showed that percentage of positivity increase in middle Egypt than other localities of Egypt.