ABSTRACT
The present study was designed to investigate the effects of protein and chromium intake on some nutritional and biological status in streptozotocin induced diabetic rats. This study was conducted on forty -nine Sprague –Dawley adult male rats, weighting 190 ±15 g were classified into control and six treated groups with drug, chromium, high protein, low protein, high protein with chromium and low protein with chromium groups for ten weeks.
The obtained results revealed that the drug, chromium, high protein, high protein with chromium and low protein with chromium groups rat group had a significant higher values of body weight gain, feed efficiency ratio, insulin, hemoglobin, packed cell volume, GPX, SOD and globulin and a significant lower value in ALT, AST, AP,γGT ,creatinine and urea when compared with control group but a significant decrease in the value of glucose and MDA compared with drug group .
The high protein and high protein with chromium rat groups showed a significant increase in the value of total protein but high protein with chromium and low protein with chromium rat groups showed significant decrease in the value of albumin/ globulin ratio when compared with control group or with drug rat group.
The chromium, high protein, high protein with chromium and low protein with chromium rat groups showed significant decrease in the value of total bilirubin while the chromium, low protein and low protein with chromium rat groups showed significant decrease in the value of uric acid when compared with control group.
The low protein rat group showed a non significant difference in final weight, weight gain, feed intake, feed efficiency ratio, insulin, packed cell volume, SOD , MDA, ALT, AST, AP , γGT, total bilirubin and creatinine and a significant decrease in glucose and GPX but a significant increase in heamoglobin and globulin when compared with control group but showed a significant decrease in weight gain, feed efficiency ratio, insulin, packed cell volume, GPX, SOD and a significant increase in glucose, MDA, ALT, AST, AP ,γGT and creatinine when compared with drug group.
Key wards :( protein - chromium - diabetic rat).