ABSTRACT Background: Underweight is a term describing a human whose A total number of 40 patients visiting Internist Department of Kasr El – AinyHospital (a governmental hospital) in Cairo were selected for present study provided that they wore overweight or obese based on BMI. Female and male patients were at the ages of 45 - < 55 and 55 – 65 years. The weight and length of each participant measured, and BMI calculated. Data of present work collected with interviews using questionnaire composed of several forms. The 24 hours recall method used to record food intake, which was analyzed to obtain levels of nutrients. Serum biochemical and haematological analyses were also carried out. Prevalence of diabetes mellitus (DM) was much greater for females than males and raised with age. At 55 – 65 years old 50 – 70 % were inflicted with high blood pressure, at this age group 50 % of males showed low efficiency of thyroid gland being possible a cause of obesity. This accompanied by low T.S.H. With increasing of age overweight, morbid and super obesity increased on account of class II obesity. TSF, AC and AMC increased also with the development of obesity. Total calories, protein, fat and carbohydrates intakes were higher than DRI. All studied biochemical analyses except uric acid and possibly HDL indicated health disorders. Haematological analyses confirmed the deteriorated health status of overweight and obese subjects of present work.