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135591

CHEMICAL AND BIOLOGICAL STUDIES ON LEMONGRASS LEAVES AGAINST NEPHROTOXICITY IN MALE RATS

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Last updated: 04 Jan 2025

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الاقتصاد المنزلي

Abstract

Abstract The effect of different levels (10, 20 & 30%) of lemongrass dry leaves (LEMS ) on renal dysfunction rats were evaluated . Thirty six male albino rats 150±5 g were used in this study and divided into 6 groups (n=6). Rats injected with 100 mg/kg b.wt gentamicin intraperitoneally daily to induce nephrotoxicity.  The results indicated that the protective groups rats fed on LEMS levels at (10, 20 & 30%) diets showed significant higher in feed intake  (FI), body weight gain (BWG) , body weight % , total protein, high density lipoprotein cholesterol (HDL-c), total antioxidants and SOD, Whereas showed significantly lower of alkaline phosphatase , albumin, uric acid, urea nitrogen , creatinine, total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-c), very low density lipoprotein cholesterol (VLDL-c) and  tumor necrosis factor  (TNF-α) as compared to positive control group. The protective group at level 30% LEMS recorded and drug group with (α LA) the highest values of all parameters between all tested diets. Therefore, it can be concluded that the consumption of LEMS as food supplement may be considered a functional food for delay or protect risk of renal dysfunction. We suggest that the anti-inflammatory and antioxidant properties of GM were dependent on the total phenolics and flavonoid contents of the LEMS. Key words:- Nephrotoxicity, α LA, lemongrass, Gallic acid equivalents, Catechin equivalents.

DOI

10.21608/mbse.2019.135591

Authors

First Name

Shimaa

Last Name

F.A.E. Ghozy

MiddleName

-

Affiliation

Home Economics Dept., Faculty of Specific Education, Mansoura University, Egypt

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Orcid

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First Name

Nanees

Last Name

Y,A Awad

MiddleName

-

Affiliation

Home Economics Dept., Faculty of Specific Education, Mansoura University, Egypt

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Orcid

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Volume

2019

Article Issue

56

Related Issue

20215

Issue Date

2019-10-01

Receive Date

2019-09-28

Publish Date

2019-10-01

Page Start

263

Page End

278

Print ISSN

2314-8683

Online ISSN

2314-8691

Article File

MBSE_Volume 2019_Issue 56_Pages 263-278.pdf

PDF . 254.1kB

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https://mbse.journals.ekb.eg/article_135591.html

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https://mbse.journals.ekb.eg/service?article_code=135591

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9

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مقالات علمیة محکمة

Type Code

1,632

Publication Type

Journal

Publication Title

مجلة بحوث التربية النوعية

Publication Link

https://mbse.journals.ekb.eg/

MainTitle

CHEMICAL AND BIOLOGICAL STUDIES ON LEMONGRASS LEAVES AGAINST NEPHROTOXICITY IN MALE RATS

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Article

Created At

23 Jan 2023