Obesity is disease life ‑threatening human; therefore, the aim of use leaves from different herbs as the leaves from mallow (Malva parviflora), sage (Salvia officinalis) and senna (Cassia angustifolia) to reduce the obesity in rat groups fed on the mixture of these herbs al level 5.0 and 10.0% and other groups were taken orally at level 50.0 and 100.0 mg/kg rat/ day from the mixture in these herds. Biological and histological experimental were determined in different obesity rat groups and compared with control negative and positive.
At the end of biological experimental (six week period of experimental) the results showed that the gain body weights and in the obesity different groups were decreased than control positive and nearly from control negative.
The results from glucose and lipid profile showed that the highest in control positive in glucose, triglycerides, total cholesterol and LDL and the lowest in control negative, whilst, the HDL was oppositely results. The results from obesity rat groups were taken the mixture herbs orally at 50 and 100 mg/kg rat/ day give the best results than other groups. Moreover the liver and kidney functions in obesity rat groups were taken orally from the mixture herbs extract at level 50 and 100 mg/kg rat/ day led to improvement the parameters on liver and kidney followed by the obesity rat groups fed on 5.0 and 10% from the mixture herbs. The results from the histological experiment showed that the obesity rat organs as heart, spleen, liver, and kidney were confirmed the previous results and preservation of the different organs.
It could be concluded and recommended that the different herbs are improvement the parameters of lipid profile, liver and kidney functions in the obesity different rat groups may be due to these herbs had contained rich amounts of polyphenolic and dietary fiber.
Keywords: mallow (Malva parviflora), sage (Salvia officinalis) and senna (Cassia angustifolia ,obesity rats