Background: Interstitial lung diseases comprise more than 200 rare diseases, which are
characterized by varying degrees of inflammations and fibrosis of the lung, and are associated with
serious quality of life impairments in affected people. Aim of study: Was to assess health related
quality of life among patients with interstitial lung disease. Research design: A descriptive research
design was utilized to conduct this study. Setting: The study was conducted at the Chest OutPatient Clinics at Benha University Hospital and Chest Hospital in Benha City. Sample: A
convenient sample of 70 patients with confirmed diagnosis. Tools: Two main tools were used I: A
structure interviewing questionnaire which included 5 parts a) socio-demographic characteristics of
patients with interstitial lung disease, b) Medical history of patients. C) Home environment of
patients, d) Knowledge of patients regarding interstitial lung disease and e) Reported practices of
the studied patients with interstitial lung disease II: Quality of life scale was adopted to assess
physical, psychological and social domains of quality of life. Results: 38.6% of patients had poor
total knowledge score about interstitial lung disease. On the other hand, 52.9% of them had
satisfactory total practices score toward interstitial lung disease. Regarding quality of life 52.9% of
patients had low quality of life and only 7,1% of them had good quality of life. Conclusion: There
were statistically significant relations between total knowledge, practices and quality of life score of
the studied patients and their educational level. There was a statistically significant correlation
between total quality of life of studied patients and their total practices. While there was highly
statistically significant correlation between the studied patients' total knowledge and their total
practices. Recommendations: Educational programs should be conducted at Out- patients Clinics
to improve knowledge, practices and quality of life of patients with interstitial lung disease