Background: Myocardial Infarction (MI) is a common presentation of ischemic heart disease. Aim of study: Was to evaluate effect of an educational program on self efficacy for patients with myocardial infraction. Research design: Quasi experimental study was utilized to conduct the aim of the study. Setting: This study was conducted at Coronary Care Unit   (CCU  (in Benha University Hospital. Sample: Purposive sample consisted of 70 patients with myocardial infarction admitted to CCU. Tools for data collection: (1) structured interviewing questionnaire including (demographic data, present illness, illness related data, daily habits sheet and patient's learning need tool) (2) self efficacy scale and cardiac exercise self scale. Results: There was increase in the mean score of patient's knowledge (study group) immediate post and after 3 months of program implementation with highly statistical significance than control group. Also there was high self efficacy of study group after 3 months of program implementation, while there was low self efficacy with control group.  Conclusion: Educational program improve self efficacy of the patient. Recommendations: Further studies should be evaluating self efficacy on other cardiac diseases.