Background: Heart surgery and Coronary catheterization are improved the medical management of cardiac diseases, which, causes a stress, anxiety and depression for patients. All these factors affect patient's quality of life before heart procedures. Aim of the study: This study aimed to assess the psychological problems and quality of life among patient undergoing heart procedures. Research Design: A descriptive design was utilized in this study. Setting: The study was conducted at cardiac department and cardiac catheter unit at Benha university hospital in Benha city, Kaluobia Governorate. Sample: A convenience sample consisting of 100 patients undergoing heart procedures. Tools of data collection: In this study three tools were used for data collection: I) A structured interviewing questionnaire included socio-demographic data and clinical data. II) Depression, Anxiety and Stress Scale (DASS-21) and III) Quality of Life Scale (QOLS). Results: Less than half of the studied patients had mild depression. Furthermore, less than half of the studied patients had extremely severe anxiety, less than one third of patients had severe stress. More than half of the studied patients had moderate level of quality of life and less than half of patients had low of quality of life. Also, there was highly statistically significant negative correlation between total depression, anxiety, and stress and total quality of life among the studied patients. Conclusion: Patients who are undergoing heart procedures are more prone to have psychological problems such as:  Depression, anxiety and stress and moderate level of quality of life, where patients who have psychological problems are likely to have impair quality of life. Recommendations: Psycho-educational programs should be integrated as nursing intervention for patients before surgery to enhance their psychological well-being and quality of life. Liaison psychiatric nurse must be available to deal with psychiatric problems of those patients.