Background: Painless labor refers to relieving labor pain via different methods of pain relief whether was pharmacological or non-pharmacological methods of pain relief. Aim of the study: Was to assess knowledge and attitudes of pregnant women regarding painless labor.Study design: Adescriptive study was utilized. Setting: This study was conducted at Obstetrics &Gynecology department at Benha University Hospital (Outpatient Clinic).Sampling:A purposive sample of 150 women who fulfill the inclusion criteria. Tools of data collection: Two tools were used for data collection; Tool I An interviewing-administered questionnaire sheet including two parts; (socio-demographic data and maternal knowledge assessment questionnaire regarding painless labor), tool II Modified Likert's scale to assess attitude of pregnant women regarding painless labor. Results: More than half of the studied women had poor knowledge and negative attitude regarding painless labor. Conclusion: There was a highly statistically significant positive correlation between total knowledge and attitude scores regarding painless labor   Recommendations: Designing and applying educational classes for the health care provider and women about painless labor at different antenatal clinics.