Background: Joint commission international hospitals accreditation aims to improve quality of health care in the international community by providing worldwide accreditation system that include highest standard of quality. Health care organizations can seek accreditation as a self-regulated step for upholding standards in healthcare system, in addition to ensuring compliance and improvement The study aimed to identify  the effect of  joint commission international  hospitals  accreditation on quality of health care as perceived by  nurses. Study design Descriptive design was utilized to meet the aim of this study. Setting this studywas conducted in all inpatients departments at El Araby hospital at Menofia Governorate. The study sample was composed of 206 staff nurses from the above mentioned setting. Two tools were used for data collection;Perceived impact of hospital accreditation outcomes questionnaire and Quality of health care questionnaire. Results The majority of study subjects (97.6%)  perceived positive outcomes of joint commission international hospitals accreditation, the majority of study subjects (84%)  perceived  satisfactory  level of quality of health care and total mean score , standard deviation regarding total quality of health care was(90.05±21.71) that represented (85.8 %) of the total score. Conclusion This study concluded that there was a significant positive correlation between outcomes of joint commission international hospitals accreditation and total level of quality of health care. The study recommended that increase nurse participation in decision making process to enhance their confidence, patientsꞌ satisfaction should be involved as a tool to measure quality.