The disruption caused by the COVID-19 pandemic worldwide has resulted in numerous impacts on the environment and the climate. As a result of the Covid-19 pandemic; water bodies, the atmosphere and ecosystems are all affected, and have experienced significant positive and negative impacts. Human health during this pandemic is the primary concern to address. Environmental systems, including water, have perceived positive impacts as a result of the reduction of pollutant loading from input of vehicle emission, and industries. This result to also, reduction in coliform and biochemical oxygen demand in rivers and lakes. Moreover, positive impacts, including air quality improvement as a result of a reduction in the loading of particulate matter, nitrous oxide, and other gaseous pollutants. In this study, we will discuss the role of different environmental factors and conditions in COVID-19 transmission, and their effect on human health.