This work provides a theoretical investigation to study the effect of different operational parameters on the
performance of TE cooling system including the system COP and the rate of heat transfer. The parameters
investigated are, the applied input power, inlet working fluid velocity, the arrangement of utilized TECs modules and
fluid type. The geometry is created with ANSYS multi-physics software as a two-dimensional base case, it is
consisted from two attached horizontal ducts of length (520 mm) and (560 mm), the interface surface between the two
ducts contains three thermoelectric modules (4 mm height by 40 mm wide and 40 mm length). The distance between
two consecutive thermoelectric modules (150 mm), the inlet and outlet duct diameter (15 mm) and the height of each
duct (10 cm), the inlet voltage to thermoelectric modules ranges from 8.0 V to 12 V and the water inlet velocity to the
two ducts from 0.001 to 0.01 m/s. Theoretical results showed that the overall COP of TE cooling system is increased
with the applied input power up to 8.0 W then it decreases with input power up to 18 W after that it takes nearly a
constant value, a noticeable enhancement in the COP is found when the three TECs are in use (Case 10) and the COP
of TE cooling system using pure water and nanofluid with 0.05% of nanoparticles as coolants takes the maximum
value.