The purpose of this research is to examine the mediating effect of university entrepreneurial intention in the relationship between Entrepreneurship education and student entrepreneurial climate. Entrepreneurship is an important source of job creation, innovation, and sustainable economic development overall countries. university students are considered the most promising source of entrepreneurs. Consequently, governments across the world take entrepreneurship as a priority to build an entrepreneurial system ranging from policy supply, support, entrepreneurship education, and atmosphere creation to encourage college students to start out a venture. The research conducted was based on a structured questionnaire was distributed on a sample of 201 students in Egyptian universities both public and private. Correlation and regression analyses were performed to test the research hypotheses. The results demonstrate a significant positive effect of Entrepreneurship education on Student's intention towards being an entrepreneur in the future. At the same time, there is a significant negative effect of the mediating role of the university entrepreneurial climate in the relationship between entrepreneurship education and student intention. This research should support universities in Egypt to increase the awareness of the students towards the importance of entrepreneurship and provide them with entrepreneurship education. It contributes to the literature by considering it as one of the growing empirical studies that will tackle the role of entrepreneurship education in both public and private universities in Egypt. The research results will support researchers and practitioners in gaining insights into the future impact of entrepreneurship education in Egypt.