Abstract:
Alcoholic leaves extracts of six species belong to genus Jatrtopha (J. integerrima Jacq, J. integerrima Rosea, J. multifida Linn, J. curcas Linn, J. gossypifolia Linn and J. pandurifolia Andrews) were screened for their total phenolic and flavonoid contents along with evaluation of their in-vitro antioxidant and anti-inflammatory properties. The total phenolic and flavonoid contents were calculated as mg of gallic acid and quercetin equivalents (GAE & QE) / g dry extract by a colorimetric method utilizing Folin-Ciocalteu reagent and AlCl3, respectively. The highest phenolic content was found in J. gossypifolia L. extract (11.21), followed by J. curcas L. (9.14), J. integerrima Jacq (5.01), J. multifida L. (4.26), J. pandurifolia Andr. (3.40) and J. integerrima Rosea (2.16). Moreover, J. gossypifolia L. recorded the highest flavonoid content (7.05), followed by J. curcas L. (6.33), J. integerrima Jacq (3.01), J. pandurifolia Andr. (1.25), J. multifida L (0.98) and J. integerrima Rosea (0.25). Concerning the biological evaluation, DPPH radical scavenging assay and membrane stabilization method were used to determine the antioxidant and anti-inflammatory activities of plant extracts, respectively. The J. gossypifolia L. has shown the best antioxidant activity (94.4%) followed by J. curcas L. (92.5%), J. integerrima Jacq (88.3%), J. multifida L. (73.5%), J. pandurifolia Andr. (66.9%) and J. integerrima Rosea (56.1%).