This research is a part of an integrated study of Sednaoui El-Khazendar building in Khedival Cairo dating back to 1913. In the first part of this study, presented in another paper, the building was inspected, the causes and symptoms of damage were identified and proposals for conservation and re-use were developed. In this paper, the studies carried out on the building's surroundings are presented. This area suffers from the random spread of street vendors, traffic overcrowding, high pollution, lack of appropriate road signs and many neglected or misused historical buildings. Among the proposals given to solve these problems and improve the situation are: the reorganization of the existence of street vendors imitating similar cases in other countries such as France and Italy; the reuse of the neglected historical buildings in an integrated way that goes along with the proposal of reusing Sednaoui building itself and adding sufficient traffic signs in streets.