Background: One of the greatest prevalent chronic illnesses, Helicobacter pylori (H. pylori), affects around 50% of people globally. Early infancy is when this virus is most often contracted, particularly in developing nations. The frequency of H. pylori varies greatly across nations; in underdeveloped nations, 50% of children are infected by the time they become 10 years old. The beginning of several Gastro intestinal tract pathologies, including active persistent gastritis, peptic ulcers, gastric carcinoma, extra-gastric symptoms, thrombocytopenic purpura, and anemia owing to inadequate iron reserves iron deficiency anemia (IDA), is discovered to be related with H. Pylori infections. A link between anemia and H. pylori infections is supported by a variety of data from epidemiological and clinical research. Objectives: To highlight connection between Helicobacter pylori infections and IDA in children, and to explore the mechanism of this association. Conclusion: Infection with Helicobacter pylori is substantially linked with iron deficiency anemia in children.