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258677

Effect of nasal corticosteroid on cacosmia after COVID-19

Article

Last updated: 27 Dec 2024

Subjects

-

Tags

Otolaryngology.

Abstract

Background: Olfactory disorders may be an isolated symptom of (COVID-19) infection.  Multiple treatment modalities have been attempted to treat them.
Objectives: compare the effect of nasal corticosteroid on COVID-19 positive patients aiming to decrease the duration of olfactory qualitative, quantitative and residual abnormalities as cacosmia with those who hadn't taken nasal corticosteroid
Patient and methods: This study included 200 patients who presented to the Otorhinolaryngology Department, divided into equal two groups: Group1 (treated group) All patients were given two sprays (50 mcg of mometasone furoate in each spray) in each nostril twice daily (total daily dose of 400 mcg). Group 2 (untreated group) those who weren't administered nasal corticosteroid or systemic corticosteroid in anosmia treatment.
Result: Anosmia in group 1 improved by 61% in the first week,83% in the second week,100 % after one month, and regular follow-up was done for 6 months while in group 2 improvement was 42% in the first week,59% in the second week,73% after one month .In group 2 out of 100 patients 30 patients  complained of cacosmia after initial anosmia 3 of them reported improving smell after 1 week then 2 weeks later cacosmia appeared and none of them were improved within the 6 months of follow up with significant p-value between 2 groups <0.001.
Conclusion: Cacosmia in the COVID-19 patient must be taken seriously with the trial of different lines of treatment. Nasal corticosteroid is highly recommended in treating anosmia in COVID-19 patients and preventing a high recurrence

DOI

10.21608/svuijm.2022.149179.1336

Keywords

COVID-19, anosmia, cacosmia, steroids

Authors

First Name

Usama

Last Name

Taya

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

usakakamal81@gmail.com

City

qena

Orcid

-

First Name

Ahmed Gaber

Last Name

AbdElraheem

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

gaboor68@gmail.com

City

-

Orcid

-

First Name

Nehad Hassan

Last Name

Abdelrahman

MiddleName

-

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

nehadhassan918@gmail.com

City

-

Orcid

-

Volume

5

Article Issue

2

Related Issue

31287

Issue Date

2022-07-01

Receive Date

2022-08-16

Publish Date

2022-07-01

Page Start

461

Page End

469

Print ISSN

2735-427X

Online ISSN

2636-3402

Link

https://svuijm.journals.ekb.eg/article_258677.html

Detail API

https://svuijm.journals.ekb.eg/service?article_code=258677

Order

45

Type

Original research articles

Type Code

1,520

Publication Type

Journal

Publication Title

SVU-International Journal of Medical Sciences

Publication Link

https://svuijm.journals.ekb.eg/

MainTitle

Effect of nasal corticosteroid on cacosmia after COVID-19

Details

Type

Article

Created At

23 Jan 2023