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152346

Left Ventricular Dysfunction in Prediabetic Patients: A review article

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Internal Medicine.
Laboratory medicine.

Abstract

Background: Prediabetes is a common condition that indicates a state between normal glucose metabolism and diabetes. This is considered a dangerous condition because of the high risk of developing diabetes. A recent study in Europe shows that visually impaired fasting increases glucose and impaired glucose tolerance. prevalence of impaired fasting glucose (IFG) levels range from approximately 3%to 5% in the 20 -44 age group and approximately 20% to 30% in the 65-74 age group. Evidence suggesting a link between the risk of neuropathy, nephropathy, early retinopathy, and macrovascular disease and prediabetes. Prediabetes is associated with a 20% increased risk of cardiovascular disease compared to normoglycemic individuals. Several studies have established systolic and diastolic left ventricular dysfunction in prediabetic patients. We aimed to highlight left ventricular dysfunction in Prediabetic patients and to describe the possible underlying mechanisms of this association.
Conclusion : There is a significant association between left ventricular systolic and diastolic dysfunction and prediabetes. The defects underlying prediabetes which include insulin resistance, metabolic syndrome, dyslipidemia, and inflammation, have been implicated to predispose diabetic patients to  increased risk of developing ventricular dysfunction.

DOI

10.21608/svuijm.2021.63389.1088

Keywords

Prediabetes, left ventricular dysfunction, echocardiography

Authors

First Name

Mohamed A.

Last Name

Elsenbsy

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, Egypt & Internal Medicine Department ,Arabian Gulf University(AGU),Bahrain

Email

alsenbsy@web.de

City

-

Orcid

-

First Name

Ahlam M.

Last Name

Sabra

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

drahlamsabra@yahoo.com

City

-

Orcid

-

First Name

Abdulla Eliaw Mohamed

Last Name

Ali

MiddleName

-

Affiliation

Department of Clinical Pathology, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

guide2-2009@med.svu.edu.eg

City

-

Orcid

0000-0001-8243-7780

First Name

Gehad Osama Fawzy

Last Name

Sayed

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

gehadosama1122@gmail.com

City

Qena

Orcid

-

First Name

Hossam Eldin M.

Last Name

Mahmoud

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, Egypt.

Email

dr-hossam-ismail@yahoo.com

City

-

Orcid

-

Volume

5

Article Issue

1

Related Issue

28020

Issue Date

2022-01-01

Receive Date

2021-02-15

Publish Date

2022-01-01

Page Start

261

Page End

267

Print ISSN

2735-427X

Online ISSN

2636-3402

Link

https://svuijm.journals.ekb.eg/article_152346.html

Detail API

https://svuijm.journals.ekb.eg/service?article_code=152346

Order

28

Type

Reviews Articles.

Type Code

1,521

Publication Type

Journal

Publication Title

SVU-International Journal of Medical Sciences

Publication Link

https://svuijm.journals.ekb.eg/

MainTitle

Left Ventricular Dysfunction in Prediabetic Patients: A review article

Details

Type

Article

Created At

23 Jan 2023