On March 11, 2020, the outbreak caused bySARS-CoV-2 that is identified as the coronavirus disease 2019 (covid-19) was considered as global pandemic. Covid-19pandemic has wide spread worldwide. The risks, morbidity and case fatality of covid-19 are associated with chronic diseases such as cardiac, renal diseases and diabetes mellitus. Recent studies reported that individuals with type1 and those with type2 diabetes are at risk of sever covid-19. The reasons for poor outcome in diabetic patients may be due to multiple factors as longstanding diabetes, old age, obesity and comorbidities such as cardiac disorders. Anti-hyperglycemic drugs can increase the risk. Sever covid-19 can be worsening factor for individuals with diabetes. Covid-19 may lead to dysregulation of blood glucose in individuals with diabetes above that caused by stress hyperglycemia.  It may cause acute metabolic complications such as diabetic ketoacidosis. This review discussed the interactions between novel coronavirus infection and diabetes mellitus.The comprehension of this association can help face covid-19 pandemic and future challenges.
Conclusion: Diabetes mellitus is related with high risk for occurrence and prognosis of covid-19 infection. There is several studies proved that diabetes increases viral entry into the cell and inflammatory reaction to the infection. This is necessary to regulate the glucose level in diabetic patients with SARS-CoV-2. Patient with mild covid-19 must be under medical advice. Diabetic patients with sever covid-19 must be hospitalized.