Background: One-lung ventilation (OLV) is a common practice during thoracic surgery
involving pulmonary resection to facilitate surgical exposure. For long time, arterial
hypoxemia during OLV was is the most important problem for the anesthesiologist. At
present, there is increasing concern about the effects of ventilator settings on acute lung
injury.
Objectives: The aim of this study is to compare the effect of different levels of Positive end
expiratory pressure (PEEP) on hemodynamics in thoracic surgeries in adult patients.
Patients and Methods: This is a prospective study that included 60 adult patients undergoing
elective thoracic procedures requiring one-lung ventilation through a posterio-lateral
thoracotomy at cardio-thoracic surgery department in Qena university hospital “between
October 2017 to April 2019", the Sixty patients were assigned to three groups: group I
received no PEEP (n = 20),group II received a PEEP (5 cmH2O) (n = 20),and group III
received a PEEP (10 cmH2O) (n = 20). Patient hemodynamics, pulmonary mechanics, and
arterial blood gases were measured just after OLV(T1) and 20 (T2), 40 (T3), and 60 min(T4)
after OLV.
Results: All cases were completed successfully. The heart rate and mean arterial blood
pressure showed no significant changes between all groups.
Conclusion: During OLV, mechanical ventilation with PEEP 0, 5 or 10 cmH2O has no effect
on hemodynamics in thoracic surgeries in adult patients.