Background:Laparoscopic cholecystectomy is a commonly performed surgery that is
associated with pneumoperitoneum‑induced respiratory compromise and altered pulmonary
mechanics strategies have been investigated for use during laparoscopic cholecystectomy. The
Objectives: to study the effects of low tidal volume with positive end-expiratory pressure
(PEEP) on arterialblood gases of patients undergoing laparoscopic cholecystectomy.
Patients and Methods: This is a prospective study that included 60 adult patients undergoing
elective laparoscopic cholecystectomywith BMI< 30at general surgery department in Qena
university hospital “between October 2016to April 2018", the Sixty patients were assigned to
two groups:group Athe tidal volume was 6 mL/kg, with PEEP of 5 cm of H2O(n = 30), group < br />B received the tidal volume was 10 mL/kg, and the PEEP was set at 0 cm of H2O (n = 30).
Patient hemodynamics, pulmonarymechanics, and arterial blood gases were measuredpreoperative,
intraoperative and post-operative.
Results:All cases were completed successfully.Study showed significance between
oxygenation in both groups. Post-operative oxygenation in protective ventilation (group < br />A)Mean Post P aO2 in group A was 91.1(± 5.1)mmHg, while in group B was 80.2(±4.2)
mmHg, p value (0.001).
Conclusion:Study found that protective ventilation was superior to conventional ventilation as
it was associated with better oxygenation in the post-operative in laparoscopic
cholecystectomy