Abstract Digital healthcare has emerged as the result of digital transformation, which offers unique opportunities to strengthen health systems and meet different challenges responding to change health need, such as the current epidemics of infectious and chronic disease. Although that, the health sector in Egypt is still lags behind other industries in seizing the opportunities brought by digital technologies, in spite of the considerable efforts and some promising national success, the health systems are still have not undergone fully digital transformation, such as: Different datasets and services still are not linked electronically together, hindering the flow of crucial information, The use of telehealth and mobile health is still limited, and The use of analytics employing diverse data and technologies such as artificial intelligence (AI) is only slowly emerging, in spite the complexity of health sector processes and activities and the ensuring high reliance on multifaceted information to solve problems. The barriers are not only technical, but also institutional and organizational. While governmental bodies need to commit to continuous investment in interoperability of flexible digital architecture, to allow for AI systems and applications as well as ensure timely modernization of policy and governance frameworks. This work outlines how current usage and what role could Egypt undertake  of digital technologies that can help to address existing and emerging health policy challenges, and how far Egypt is in seizing the opportunities of digitalization and AI through the following domains: Providing an overview of the most prevalent use technologies in health sector, i.e., electronic data communication systems, Discussing telehealth and mobile health(mHealth) solutions, such as robot assistant therapies or novel devices that allow diagnostics and therapy at home, Identifying current use of existing data and interoperability across segments of health systems as related to Egypt, Describing developments in automation, data-driven, prediction, and decision support, including technologies such as adequate digitization and artificial intelligence that support digital healthcare, The work concluded the results and recommendations for Egyptian healthcare.