ABSTRACT The efficient management of big cities requires the knowledge and the integration of the several data necessary to describe the huge number of variables that govern the urban environment evolution. In developing countries, where the resources are scarce or in-homogeneously distributed, the problem of acquiring reliable data is amplified by the local  conditions and the integration of data of different nature can be extremely complicated without appropriate instruments. In the 21st century, almost all public organizations have started to use Information Technologies in Egypt, and the municipalities have been utilized technological. The increasing demands in urban planning and management sectors call for GIS for sustainable development of urban areas. Geographical Information System (GIS) is used as a tool in the World especially developing countries in order to get right decisions and arrange the urban facilities. In the past, information systems for health sector were designed for use centrally with little or no feedback to the source of information and with no impact on local activities. The information systems are a vital element for strengthening the national and local capacities for assessing the situations, for selecting appropriate control measures, and for adapting activities to changes in the situation developments as a tool for their services. Modern tools like remote sensing and Geographical Information Systems (GIS) have now come in handy to address the issues in support data collection, storage, distribution as well as the public participation processes for health sector In this paper, we present a case study for using GIS as tools in the redistribution of public health centers in some crowed areas in Cairo Egypt taking in account the distribution of population in these crowed areas. In order to sustainable development in health sector in Egypt and public centers and redesign these public centers.