Abstract: Background: It is essential for health care organizations to keep positive working conditions in order to keep their talent nurses and help them to work hard. Purpose: To investigate the relationship between nurses` work practice environment and their organizational commitment. Design: A descriptive correlational design was used in this study. Setting: The study was conducted in Fevers hospital at Shebin El-Kom. It included (ICU units, pediatric, medical, pandemic, obstetrics, surgical operations, liver units, thoracic, hemodialysis, PICU).Subjects: Included 284 nurses from accepted the participation in the study and have at least one year of experience. Data collection instruments: The practice environment scale of the nursing work index and organizational commitment questionnaire. Results: the highest percent of the studied nurses considered their work environment as a good environment, the lowest percent of studied nurses considered their work environment as a poor work practice environment. On other hand, the majority of the studied nurses revealed high level of organizational commitment, about one quarter of the studied nurses have moderate level of organizational commitment. While, only few proportion of the studied nurses reveal low level of organizational commitment. Conclusion: It demonstrated that there was a high statistically significant positive correlation between nurses` work practice environment and their organizational commitment. Recommendations: Providing a comfortable workplace and supportive work facilities are important factors for nurses positive work environment and help them to be committed.