Wound healing is accelerated and improved by using honey dressing due to its antioxidant, anti-bacterial and anti-inflammatory properties. Purpose: to determine the effect of honey dressing on open wound healing and the length of stay among surgical patients.  Design: A quasi-experimental design was utilized for this study. Setting: General surgical department of menoufia university hospital.  Sampling: A purposive sample of 90 adult patients with open wound, were selected and divided alternatively and randomly into two equal groups (45 study group and45 control group). Instruments: Bates-Jensen wound assessment Likert Scale was used. Results: There was significant improvement in wound healing among study group than control group. Moreover there were statistical significant differences between both groups regarding length of stay at hospital The mean length of stay (days) of the study group was 9.31 ±2.77 ranging from 4 days to 16 days of the control group was 16.84 ± 6.45 ranging from 7 days to 30 days. Conclusions: The honey dressing was safe and effective on wound healing and didn't cause any side effects, accelerate wound healing and decease length of hospital stay. Recommendations: Honey dressing should be used as an alternative therapy for wound healing as it is safe, cost effective, accelerate wound healing, and promote patient comfort.