Background: Spiritual leadership can guide leaders to help followers to be able to meet higher order needs. Purpose: Is to explore the relationship between spiritual leadership and organizational trust among nurses. Design: A descriptive correlational design was used in this study. Setting: the study was conducted at Menoufia university hospitals all 11 ICU units, all 6 operation room, all 21deparetments and 15 out patients clinics. Subjects: included all nursing managers were available 85 at the time of the study, 400 staff nurses were selected by simple random sample to participate in the study. Data collection Instruments: spiritual leadership and organizational trust questionnaire. Results: the highest percentage of nursing managers' perception was observed between moderate and high level of spiritual leadership. The highest percent of staff nurses had low levels of organizational trust dimensions while the lowest percent of staff nurses had high levels of organizational trust dimensions. Conclusion: there was positive statistically significant correlation between nursing managers' altruistic love levels and staff nurses' organization's trust dimension. Also there was positive statistically significant correlation between nursing managers' membership levels and staff nurses' nursing managers' trust dimension and staff nurses' organizational trust dimension and the medium score of staff nurses' organizational trust levels increased with increase of nursing managers' levels of spiritual leadership medium score. Recommendations: the nursing managers should use the application of innovative styles such as spiritual leadership to improving the organizational trust among staff nurses