The peripherally inserted central catheters (PICCs )have become among the most
common technologies employed in the intravenous therapy of neonates as they allow safe
long-term intravascular access, comfort, and ease of transition to home therapy that
contributed to the increased survival of those newborns. Aim: Assess the nurses'
knowledge and practices about peripherally inserted central catheter at neonatal intensive
care units Method: Descriptive research was conducted on 45 neonatal nurses working at
neonatal intensive care units affiliated to Mansoura University Children Hospital (MUCH).
Peripherally inserted central catheter insertion questionnaire sheet and observational
checklistwas used to collect data. Results: Most studied nurses had poor knowledge and the
minority had average knowledge about PICC line care for neonates. Also, more than half
of nurses had competent score regarding PICC line insertion and care. Conclusion: There
was variation regrading neonatal nurses' knowledge and practices regarding PICC line
insertion and care. Recommendation: A regular educational program about PICC line
care should be consistent for neonatal nurse