Background: Chemotherapy-induced nausea and vomiting (CINV) remains a significant reason of distress and dissatisfaction among patients getting cancer treatment. Aim: The aim of this study is to assess the effect of ginger tea on chemotherapy induced nausea and vomiting in women with cancer. Study Design: A quasi-experimental research design. Sampling: A purposive sample of 100 women with gynecological and breast cancer. Setting: This study was conducted at the outpatient clinics of oncology and nuclear medicine department affiliated to Ain Shams University Hospital. Tools: Three tools were used for the data collection of this study I. A Patient interview questionnaire included patients‘ demographic and clinical data, II. Simplified form of Rhodes index of nausea, vomiting and retching assessment scale. III. Patients ‗satisfaction questionnaire Results: The mean age of all patients was 5.84+36.79 years, 17 (34%) of the patients in the control group had secondary educational level, while 19 (38%) in experimental group were university graduates. 35 (70%) and 36 (72%) of patients in the control group and experimental group were married. (54%, 60%) of patients in the control group and experimental group were employed. Regarding total vomiting and nausea experience score, there was no significant difference between both groups before research intervention and during the first 6, 12 & 24 hours after chemotherapy. However, there was a statistically significant association in intervention (ginger tea group) and control group on the second day, third day and fourth day post chemotherapy (p = <0.001). Conclusions and recommendations: The current study showed that ginger tea can be administered to patients with gynecologic and breast cancer as a safe herbal medicine for effective prevention of chemotherapy-induced nausea and vomiting. Prospective studies and longer periods of follow up are also helpful to assess the efficacy of ginger supplementation on the prevalence of CINV symptoms in patients receiving multiple cycles of chemotherapy.