Background: Coronary artery disease (CAD) is considered as the leading cause of mortality worldwide, elderly patients suffering CAD need educational programs aimed at promoting healthy lifestyles among them in order to improve their QoL. Aim: The study aimed to assess quality of life among elderly patients with coronary artery disease at Zagazig hospitals. Study design: A cross sectional descriptive design was used in this study. Setting: The study was conducted in the cardiology outpatient clinic at Zagazig University Hospital and Al-Mabarrah hospital at Zagazig Hospitals. Sample: A purposive sample of 165 elderly patients with coronary artery disease since at least one year and free from major illness such as uncontrolled diabetes mellitus, cancer and renal failure. Tools of data collection: A tool was used for data collection was consisted into two parts which included demographic characteristics and patient interview questionnaire quality of life. Results: The results revealed that elderly patients with coronary artery disease in the study settings have generally low quality of life. The highest median score was in sexual QoL (4.00) followed by the social QoL (3.18). On the other hand, the lowest score of QoL was in the physical QoL domain in both physical (2.08) and sleep (1.80). Conclusion: The study findings lead to the conclusion that elderly patients having generally low quality of life. This is particularly evident regarding physical QoL and sleep. Meanwhile, they have good social and sexual QoL. Recommendations: Elderly patients suffering CAD needs educational programs aimed at promoting healthy lifestyles among them in order to improve their QoL.