Diabetes related lower extremity complication increase the risk for amputation which include peripheral neuropathy, peripheral vascular disease, and infection. Peripheral arterial disease is estimated to be 2 to 4 times more common in persons with diabetes than in others . Buerger Allen exercise intended to improve feet, legs circulation and relieve the symptoms in patients with lower limbs arterial insufficiency. Therefore, the aim of the study, evaluate the effect of Burger Allen exercise on lower limb perfusion in patients with type 2 diabetes mellitus. Method and sample, Quasi-experimental research design was conducted in the diabetic and endocrine ward and diabetic foot clinic in Specialized-Medical Hospital, at Mansoura University. The sample of this study composed of 48 adult patients with type 2 Diabetes who attend the diabetic ward and diabetic foot clinic in Specialized-Medical Hospital throughout six months. Patients randomly assigned into two matched groups; study group (group A) and control group (group B). Results, indicates significant improvement into patients lower extremity perfusion by using Ankle Brachial Index ( ABI) scale after performance of Buerger Allen exercise and at the same time it helped to improve the vascularity and thus promotes the wound healing process. Conclusion, positive effect of Buerger Allen exercise on diabetic patients lower extremity perfusion.