Myoepithelial cells are observed in several exocrine glands. They are star-shaped cells that lie in between the basal lamina and the acinar and ductal cells (Ogawa et al., 1999)30. These cells have the structural features and function of both smooth muscle cells and epithelium (Franke et al., 1980)31. They contract when the gland is stimulated to secrete. They aid expulsion of glandular secretion through compressing or reinforcing the underlying parenchyma! cells, it was suggested that the major function of myoepithelial cells in salivary glands is to support the glandular structure through isometric contraction (Segawa et a!., 1995)36. They also display the characteristics of epithelium in that they are situated
within the glandular epithelium between secretory cells and the basement membrane (Tandler, 1965; Harrop, 1968; Leeson and Leeson, 1971)45,19,26
Myoepithelial cells have speculated to play an important role in histo-genesis of some salivary gland tumors, such as pleomorphic adenoma, myoepithelioma, adenoid cystic carcinoma and certain other tumors (Bat-sakis et al., 1983; Dardick and Bu-
ford-Mason, 1993; Redman, 1994) 2,9,33.
Studies of the responses of SMG to ligation of the main excretory duct have established that both acinar cells and cells of the granular ducts are markedly altered morphologically